PYUSD is unusual among stablecoins because its primary distribution channel is the PayPal app itself. US PayPal customers can buy, sell, and hold PYUSD directly inside their existing account without a separate crypto exchange relationship, which is not how USDC, USDT, or DAI reach retail. The token is issued by Paxos, the same NYDFS-regulated trust company that issues PAX Gold and previously issued BUSD.
Outside PayPal, PYUSD is listed on Coinbase, Kraken, Crypto.com, and Bitstamp, plus Uniswap and Curve on Ethereum and several Solana DEXes. The two on-chain deployments matter. PYUSD on Ethereum is an ERC-20 with typical L1 gas costs on transfers. PYUSD on Solana is an SPL token, and Solana's fee environment makes it the clearly cheaper choice for moving size or making frequent payments.
The recurring mistake is chain mismatch. PYUSD-on-Ethereum and PYUSD-on-Solana are different token deployments with the same name. Sending PYUSD from a Solana wallet to an Ethereum deposit address at an exchange that only supports the Solana deployment results in funds the destination cannot credit. The reverse is equally broken. Some exchanges support both chains but list them as separate withdrawal options; you must pick the right one. A number of retail users have moved PYUSD out of PayPal onto the wrong chain for their destination because PayPal itself chose which chain to withdraw on for them at the time.
Before withdrawing from PayPal or any exchange, confirm the destination supports the chain the source is using. If in doubt, test with five dollars. Contract address verification on Ethereum and SPL mint address on Solana should be cross-checked against paxos.com/pyusd before interacting with any DEX.